Sheen Opens Podcast Door to Cryer and Lorre

Charlie Sheen said Jon Cryer and Chuck Lorre have an open invitation to appear on his new podcast, Mostly Sheenius. Sheen made the comments in an Entertainment Tonight interview conducted by Denny Directo and published on November 14, 2026, two days after the podcast launched.

Cryer co-starred with Sheen as Alan Harper opposite Sheen's Charlie Harper on Two and a Half Men, and Lorre co-created the sitcom. The invitation extends to both men, according to what Sheen told the outlet.

Mostly Sheenius, a weekly podcast, debuted on November 12, 2026.

Years of distance

Sheen and Cryer played the Harper brothers for eight seasons between 2003 and 2011. Sheen was fired from the sitcom amid a public feud with Lorre.

In February 2024, Cryer said on The View that he was glad Sheen seemed to be doing better, but that he was unsure about working with him again for any length of time. Cryer has more recently discussed reconnecting with Sheen after contributing to his Netflix documentary, and Sheen appeared in Lorre's 2023 Max series Bookie.